InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: YWHAQ

Summary

InnateDB Gene

IDBG-638322.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

YWHAQ

Gene Name

14-3-3 protein theta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002108

Encoded Proteins

IDBP-690388

14-3-3 protein theta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134308:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99%% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5\' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:87842280-87873674

Strand

Forward strand

Band

Transcripts

ENSBTAT00000032851

ENSBTAP00000032779

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 247 interaction(s) predicted by orthology.

Predicted by orthology
Total	247 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0047485	protein N-terminus binding

Biological Process

GO:0006605	protein targeting
GO:0007264	small GTPase mediated signal transduction
GO:0021762	substantia nigra development
GO:0045892	negative regulation of transcription, DNA-templated
GO:0055114	oxidation-reduction process