InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.58992

Summary

InnateDB Gene

IDBG-638451.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.58992

Gene Name

C-Jun-amino-terminal kinase-interacting protein 4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012293

Encoded Proteins

IDBP-690541

C-Jun-amino-terminal kinase-interacting protein 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000008294:
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:36343607-36422982

Strand

Forward strand

Band

Transcripts

ENSBTAT00000016326

ENSBTAP00000016326

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008432	JUN kinase binding
GO:0019894	kinesin binding
GO:0048273	mitogen-activated protein kinase p38 binding

Biological Process

GO:0000187	activation of MAPK activity
GO:0007257	activation of JUN kinase activity
GO:0030335	positive regulation of cell migration
GO:0042147	retrograde transport, endosome to Golgi
GO:0043410	positive regulation of MAPK cascade
GO:0045666	positive regulation of neuron differentiation
GO:0051146	striated muscle cell differentiation
GO:0051260	protein homooligomerization
GO:0090074	negative regulation of protein homodimerization activity