Bos taurus Gene: MED21
Summary
InnateDB Gene IDBG-638697.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED21
Gene Name Mediator of RNA polymerase II transcription subunit 21
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005082
Encoded Proteins
Mediator of RNA polymerase II transcription subunit 21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152944:
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:83186276-83196046
Strand Reverse strand
Band
Transcripts
ENSBTAT00000006696 ENSBTAP00000006696
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.
Predicted by orthology
Total 59 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0001824 blastocyst development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019827 stem cell maintenance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Transcriptional regulation of white adipocyte differentiation pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
PPARA activates gene expression pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
Transcriptional regulation of white adipocyte differentiation pathway
Mus musculus biological processes pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q2TBU8
TrEMBL
UniProt Splice Variant
Entrez Gene 539496
UniGene Bt.5469
RefSeq NM_001038566
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109636
GenPept AAI09637
RNA Seq Atlas 539496