Version 5.4
Bos taurus Gene: PKD2L1
Summary
InnateDB Gene IDBG-638738.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKD2L1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010742
Encoded Proteins
IDBP-690840
polycystic kidney disease 2-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107593:
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:21056133-21108833
Strand Reverse strand
Band
Transcripts
ENSBTAT00000014222 ENSBTAP00000014222
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005227 calcium activated cation channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005272 sodium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008324 cation transmembrane transporter activity
GO:0015269 calcium-activated potassium channel activity
GO:0033040 sour taste receptor activity
GO:0042802 identical protein binding
GO:0051371 muscle alpha-actinin binding
GO:0051393 alpha-actinin binding
Biological Process
GO:0001581 detection of chemical stimulus involved in sensory perception of sour taste
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007224 smoothened signaling pathway
GO:0035725 sodium ion transmembrane transport
GO:0050915 sensory perception of sour taste
GO:0050982 detection of mechanical stimulus
GO:0055085 transmembrane transport
GO:0070207 protein homotrimerization
GO:0070588 calcium ion transmembrane transport
GO:0071468 cellular response to acidity
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0031513 nonmotile primary cilium
GO:0034704 calcium channel complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000107593
View Gene Order
ENSMUSG00000037578
View Gene Order
Cross-References
SwissProt
TrEMBL F1N5R3
UniProt Splice Variant
Entrez Gene 521231
UniGene
RefSeq XM_002698489
HUGO HGNC:9011
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058966
GenPept
RNA Seq Atlas 101909602 521231

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca