Bos taurus Gene: ST8SIA1 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-638881.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | ST8SIA1 | ||||||||
Gene Name | alpha-N-acetylneuraminide alpha-2,8-sialyltransferase | ||||||||
Synonyms | SIAT8A | ||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000000593 | ||||||||
Encoded Proteins |
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111728:
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 5:88287352-88453869 | ||||||||
Strand | Forward strand | ||||||||
Band | |||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
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KEGG |
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
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INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | F1MRQ8 Q8WN13 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 282352 | ||||||||
UniGene | Bt.13269 | ||||||||
RefSeq | NM_001032299 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AF450088 DAAA02014105 DAAA02014106 DAAA02014107 | ||||||||
GenPept | AAL47018 | ||||||||
RNA Seq Atlas | 282352 | ||||||||