Bos taurus Gene: FIGF | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-638939.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | FIGF | ||||||||||||||
Gene Name | vascular endothelial growth factor D precursor | ||||||||||||||
Synonyms | VEGF-D | ||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000009476 | ||||||||||||||
Encoded Proteins |
vascular endothelial growth factor D
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165197:
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome X:135366419-135410968 | ||||||||||||||
Strand | Forward strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
VEGF binds to VEGFR leading to receptor dimerization pathway
VEGF ligand-receptor interactions pathway
Signaling by VEGF pathway
Platelet activation, signaling and aggregation pathway
Signal Transduction pathway
Hemostasis pathway
Platelet degranulation pathway
Hemostasis pathway
VEGF ligand-receptor interactions pathway
Signaling by VEGF pathway
Platelet activation, signaling and aggregation pathway
VEGF binds to VEGFR leading to receptor dimerization pathway
Response to elevated platelet cytosolic Ca2+ pathway
Signal Transduction pathway
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KEGG |
Cytokine-cytokine receptor interaction pathway
Focal adhesion pathway
Pathways in cancer pathway
Cytokine-cytokine receptor interaction pathway
Focal adhesion pathway
Pathways in cancer pathway
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INOH |
VEGF signaling pathway pathway
GPCR signaling pathway
VEGF signaling pathway pathway
GPCR signaling pathway
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PID NCI |
VEGF and VEGFR signaling network
VEGFR3 signaling in lymphatic endothelium
Alpha9 beta1 integrin signaling events
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | A7MBB6 Q9GLX1 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 286799 | ||||||||||||||
UniGene | Bt.13096 | ||||||||||||||
RefSeq | NM_001101043 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | AF099135 BC151466 DAAA02074886 | ||||||||||||||
GenPept | AAG29747 AAI51467 | ||||||||||||||
RNA Seq Atlas | 286799 | ||||||||||||||