Version 5.4
Bos taurus Gene: ETHE1
Summary
InnateDB Gene IDBG-639008.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETHE1
Gene Name Protein ETHE1, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004379
Encoded Proteins
IDBP-691126
Protein ETHE1, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105755:
This gene encodes a sulfur dioxygenase that localizes within the mitochondrial matrix. The enzyme functions in sulfide catabolism. Mutations in this gene result in ethylmalonic encephalopathy.[provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:52048413-52065702
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005747 ENSBTAP00000005747
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050313 sulfur dioxygenase activity
GO:0051213 dioxygenase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0055114 oxidation-reduction process
GO:0070813 hydrogen sulfide metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105755
View Gene Order
ENSMUSG00000064254
View Gene Order
Pathways
NETPATH
REACTOME
REACT_226362
Metabolism of amino acids and derivatives pathway
REACT_220773
Degradation of cysteine and homocysteine pathway
REACT_213617
Sulfide oxidation to sulfate pathway
REACT_212045
Sulfur amino acid metabolism pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116010
Sulfide oxidation to sulfate pathway
REACT_115654
Degradation of cysteine and homocysteine pathway
REACT_115639
Sulfur amino acid metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_198963
Sulfide oxidation to sulfate pathway
REACT_198964
Degradation of cysteine and homocysteine pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_202492
Sulfur amino acid metabolism pathway
KEGG
hsa00920
Sulfur metabolism pathway
mmu00920
Sulfur metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q3T094
TrEMBL
UniProt Splice Variant
Entrez Gene 509150
UniGene Bt.48849
RefSeq NM_001034344
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102496
GenPept AAI02497
RNA Seq Atlas 509150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca