Version 5.4
| Bos taurus Gene: BT.103245 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-639062.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | BT.103245 | ||||||||
| Gene Name | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000006014 | ||||||||
| Encoded Proteins |
golgi brefeldin A resistant guanine nucleotide exchange factor 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107862:
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 26:22761606-22884208 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Clathrin derived vesicle budding pathway
COPI Mediated Transport pathway
trans-Golgi Network Vesicle Budding pathway
Golgi to ER Retrograde Transport pathway
Membrane Trafficking pathway
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| KEGG |
Endocytosis pathway
Endocytosis pathway
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| INOH | |||||||||
| PID NCI |
Arf1 pathway
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BMC4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 533207 | ||||||||
| UniGene | Bt.103245 Bt.104327 Bt.6737 | ||||||||
| RefSeq | |||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02058999 DAAA02059000 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 533207 | ||||||||