Version 5.4
Bos taurus Gene: PPP1R1B
Summary
InnateDB Gene IDBG-639385.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R1B
Gene Name Protein phosphatase 1 regulatory subunit 1B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006035
Encoded Proteins
IDBP-691536
Protein phosphatase 1 regulatory subunit 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131771:
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40655222-40663767
Strand Forward strand
Band
Transcripts
ENSBTAT00000007930 ENSBTAP00000007930
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
Biological Process
GO:0001975 response to amphetamine
GO:0006351 transcription, DNA-templated
GO:0007165 signal transduction
GO:0007621 negative regulation of female receptivity
GO:0008542 visual learning
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131771
View Gene Order
ENSMUSG00000061718
View Gene Order
Pathways
NETPATH
REACTOME
REACT_205369
Signaling by GPCR pathway
REACT_205490
DARPP-32 events pathway
REACT_214353
Signal Transduction pathway
REACT_219672
Opioid Signalling pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_8
Wnt pathway
NetPath_23
TSH pathway
REACTOME
REACT_15334
DARPP-32 events pathway
REACT_15295
Opioid Signalling pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_254215
Signaling by GPCR pathway
REACT_203795
DARPP-32 events pathway
REACT_242845
Opioid Signalling pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.4706
RefSeq NM_174647
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca