Version 5.4
Bos taurus Gene: BT.20671
Summary
InnateDB Gene IDBG-639465.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.20671
Gene Name PMS1 protein homolog 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018795
Encoded Proteins
IDBP-691638
PMS1 protein homolog 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064933:
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:6395005-6511175
Strand Reverse strand
Band
Transcripts
ENSBTAT00000025019 ENSBTAP00000025019
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0030983 mismatched DNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006298 mismatch repair
Cellular Component
GO:0032389 MutLalpha complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000064933
View Gene Order
ENSMUSG00000026098
View Gene Order
Cross-References
SwissProt
TrEMBL F1MW63
UniProt Splice Variant
Entrez Gene 529491
UniGene Bt.20671
RefSeq NM_001077981 XM_005202203 XM_005202204 XM_005202205
HUGO HGNC:9121
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003905 DAAA02003906 DAAA02003907
GenPept
RNA Seq Atlas 529491

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca