InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: FUS

Summary

InnateDB Gene

IDBG-639574.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FUS

Gene Name

RNA-binding protein FUS

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005757

Encoded Proteins

IDBP-691747

RNA-binding protein FUS

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089280:
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:27523969-27533988

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007571

ENSBTAP00000007571

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.

Predicted by orthology
Total	82 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding