Bos taurus Gene: CLEC9A | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-639576.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | CLEC9A | ||||||
Gene Name | Uncharacterized protein | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000009537 | ||||||
Encoded Proteins |
C-type lectin domain family 9, member A
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
InnateDB Annotation from Orthologs | |||||||
Summary |
[Homo sapiens] CLEC9A is restricted to dendritic cells, and specifically recognizes filamentous actin from necrotic cells. CLEC9A ligand engagement is necessary for the priming of cytotoxic T cells against necrotic cell antigens.
[Mus musculus] Clec9a is restricted to dendritic cells, and specifically recognizes filamentous actin from necrotic cells. Clec9a ligand engagement is necessary for the priming of cytotoxic T cells against necrotic cell antigens. (Demonstrated in human)
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Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197992:
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 5:100328706-100340514 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | E1BKB0 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | |||||||
RefSeq | |||||||
HUGO | HGNC:26705 | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02014361 | ||||||
GenPept | |||||||
RNA Seq Atlas | |||||||