Version 5.4
Bos taurus Gene: RNF11
Summary
InnateDB Gene IDBG-639645.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF11
Gene Name RING finger protein 11
Synonyms Sid1669
Species Bos taurus
Ensembl Gene ENSBTAG00000012996
Encoded Proteins
IDBP-691823
RING finger protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123091:
The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:95599737-95601983
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017277 ENSBTAP00000017277
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 65 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 65 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051865 protein autoubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0055037 recycling endosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000123091
View Gene Order
ENSMUSG00000028557
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q08DI6
TrEMBL F1MFA2
UniProt Splice Variant
Entrez Gene 522791
UniGene Bt.6666
RefSeq NM_001077953
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123728 DAAA02008904
GenPept AAI23729
RNA Seq Atlas 522791

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca