Version 5.4
Bos taurus Gene: MGC142781
Summary
InnateDB Gene IDBG-639685.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MGC142781
Gene Name carnitine O-acetyltransferase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001932
Encoded Proteins
IDBP-691871
carnitine O-acetyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095321:
This gene encodes carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:99576794-99589668
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002513 ENSBTAP00000002513
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004092 carnitine O-acetyltransferase activity
GO:0005102 receptor binding
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0019254 carnitine metabolic process, CoA-linked
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000095321
View Gene Order
ENSMUSG00000026853
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_17062
Beta-oxidation of very long chain fatty acids pathway
REACT_17017
Beta-oxidation of pristanoyl-CoA pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_16957
Peroxisomal lipid metabolism pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_247416
Beta-oxidation of very long chain fatty acids pathway
REACT_243096
Beta-oxidation of pristanoyl-CoA pathway
REACT_246750
Peroxisomal lipid metabolism pathway
KEGG
hsa04146
Peroxisome pathway
mmu04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q08DN5
UniProt Splice Variant
Entrez Gene 512902
UniGene Bt.61867
RefSeq NM_001075587 XM_005213251
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123649 BT030711 DAAA02032204
GenPept AAI23650 ABS45027
RNA Seq Atlas 512902

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca