Bos taurus Gene: EXOSC9
Summary
InnateDB Gene IDBG-639746.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOSC9
Gene Name exosome complex component RRP45
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004942
Encoded Proteins
exosome complex exonuclease RRP45
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123737:
This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:3419547-3432299
Strand Reverse strand
Band
Transcripts
ENSBTAT00000006502 ENSBTAP00000006502
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017091 AU-rich element binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0030307 positive regulation of cell growth
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0071028 nuclear mRNA surveillance
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
Cellular Component
GO:0000178 exosome (RNase complex)
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Butyrate Response Factor 1 (BRF1) destabilizes mRNA pathway
Tristetraprolin (TTP) destabilizes mRNA pathway
KSRP destabilizes mRNA pathway
mRNA decay by 3' to 5' exoribonuclease pathway
ATF4 activates genes pathway
PERK regulates gene expression pathway
Unfolded Protein Response (UPR) pathway
Deadenylation-dependent mRNA decay pathway
Metabolism of proteins pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
Gene Expression pathway
mRNA decay by 3' to 5' exoribonuclease pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
KSRP destabilizes mRNA pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
KEGG
RNA degradation pathway
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.12557
RefSeq NM_001035053
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas