Version 5.4
Bos taurus Gene: BT.49277
Summary
InnateDB Gene IDBG-639757.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.49277
Gene Name annexin A5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021746
Encoded Proteins
IDBP-691952
annexin A5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164111:
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:3542635-3575330
Strand Forward strand
Band
Transcripts
ENSBTAT00000028988 ENSBTAP00000028988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0010033 response to organic substance
GO:0050819 negative regulation of coagulation
Cellular Component
GO:0005622 intracellular
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
GO:0072563 endothelial microparticle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164111
View Gene Order
ENSMUSG00000027712
View Gene Order
Cross-References
SwissProt
TrEMBL F6QVC9 Q9N1C2
UniProt Splice Variant
Entrez Gene 281626
UniGene Bt.49277 Bt.96612
RefSeq NM_001040477
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF210382 DAAA02015231 DAAA02015232
GenPept AAF25883
RNA Seq Atlas 281626

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca