Version 5.4
Bos taurus Gene: FABP2
Summary
InnateDB Gene IDBG-639864.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FABP2
Gene Name fatty acid-binding protein, intestinal
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017045
Encoded Proteins
IDBP-692054
fatty acid-binding protein, intestinal
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145384:
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:7105321-7108886
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022662 ENSBTAP00000022662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008289 lipid binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000145384
View Gene Order
ENSMUSG00000023057
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03320
PPAR signaling pathway pathway
hsa04975
Fat digestion and absorption pathway
mmu03320
PPAR signaling pathway pathway
mmu04975
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MFF7
UniProt Splice Variant
Entrez Gene 515768
UniGene
RefSeq NM_001025332 XM_005207586
HUGO HGNC:3556
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02016284 DAAA02016285 DAAA02016286
GenPept
RNA Seq Atlas 515768

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca