Version 5.4
| Bos taurus Gene: AP2S1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-639941.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | AP2S1 | ||||||||||
| Gene Name | AP-2 complex subunit sigma | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000010584 | ||||||||||
| Encoded Proteins |
AP-2 complex subunit sigma
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000042753:
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts. [provided by RefSeq, Jul 2008] One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 18:54363679-54373314 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Signaling by Wnt pathway
Signaling by EGFR pathway
Recycling pathway of L1 pathway
Trafficking of GluR2-containing AMPA receptors pathway
Retrograde neurotrophin signalling pathway
WNT5A-dependent internalization of FZD4 pathway
L1CAM interactions pathway
Immune System pathway
Transmission across Chemical Synapses pathway
Signal Transduction pathway
Signaling by EGFR in Cancer pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Axon guidance pathway
MHC class II antigen presentation pathway
beta-catenin independent WNT signaling pathway
NGF signalling via TRKA from the plasma membrane pathway
PCP/CE pathway pathway
Neuronal System pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Signalling by NGF pathway
Adaptive Immune System pathway
EGFR downregulation pathway
Trafficking of AMPA receptors pathway
Disease pathway
Developmental Biology pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
MHC class II antigen presentation pathway
Retrograde neurotrophin signalling pathway
EGFR downregulation pathway
Signaling by EGFR pathway
Nef Mediated CD8 Down-regulation pathway
Nef Mediated CD4 Down-regulation pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
PCP/CE pathway pathway
Developmental Biology pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
WNT5A-dependent internalization of FZD4 pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Axon guidance pathway
Signal Transduction pathway
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
Adaptive Immune System pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
EPH-ephrin mediated repulsion of cells pathway
HIV Infection pathway
EPH-Ephrin signaling pathway
The role of Nef in HIV-1 replication and disease pathogenesis pathway
Host Interactions of HIV factors pathway
Disease pathway
WNT5A-dependent internalization of FZD4 pathway
EGFR downregulation pathway
Disease pathway
Signaling by Wnt pathway
Recycling pathway of L1 pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
beta-catenin independent WNT signaling pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Immune System pathway
Retrograde neurotrophin signalling pathway
PCP/CE pathway pathway
MHC class II antigen presentation pathway
Signaling by EGFR pathway
Axon guidance pathway
L1CAM interactions pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Neuronal System pathway
Developmental Biology pathway
Trafficking of GluR2-containing AMPA receptors pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
Trafficking of AMPA receptors pathway
Transmission across Chemical Synapses pathway
Signaling by EGFR in Cancer pathway
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| KEGG |
Endocytosis pathway
Huntington's disease pathway
Huntington's disease pathway
Endocytosis pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Bt.6673 Bt.89386 | ||||||||||
| RefSeq | NM_001076078 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||