InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.23508

Summary

InnateDB Gene

IDBG-640053.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.23508

Gene Name

collagen alpha-1(VI) chain precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011802

Encoded Proteins

IDBP-692269

collagen alpha-1(VI) chain

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142156:
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:147404396-147423644

Strand

Forward strand

Band

Transcripts

ENSBTAT00000015668

ENSBTAP00000015668

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0048407	platelet-derived growth factor binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0070208	protein heterotrimerization
GO:0071230	cellular response to amino acid stimulus

Cellular Component

GO:0005576	extracellular region
GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0031012	extracellular matrix
GO:0042383	sarcolemma
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome