InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: KIF2C

Summary

InnateDB Gene

IDBG-640243.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIF2C

Gene Name

kinesin-like protein KIF2C

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015280

Encoded Proteins

IDBP-692484

kinesin-like protein KIF2C

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142945:
The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. [provided by RefSeq, Jul 2008]
This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:101832373-101851108

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000020322

ENSBTAP00000020322

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0051010	microtubule plus-end binding

Biological Process

GO:0007018	microtubule-based movement
GO:0007019	microtubule depolymerization
GO:0008152	metabolic process
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
GO:0051983	regulation of chromosome segregation

Cellular Component

GO:0000775	chromosome, centromeric region
GO:0000776	kinetochore
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane
GO:0035371	microtubule plus-end