InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AGPS

Summary

InnateDB Gene

IDBG-640281.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AGPS

Gene Name

alkyldihydroxyacetonephosphate synthase, peroxisomal

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009897

Encoded Proteins

IDBP-692566

alkylglycerone phosphate synthase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000018510:
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:19340960-19433177

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000061434

ENSBTAP00000053342

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008609	alkylglycerone-phosphate synthase activity
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0008610	lipid biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle