Bos taurus Gene: EIF3A
Summary
InnateDB Gene IDBG-640287.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF3A
Gene Name eukaryotic translation initiation factor 3 subunit A
Synonyms EIF3S10; EIF6
Species Bos taurus
Ensembl Gene ENSBTAG00000002528
Encoded Proteins
eukaryotic translation initiation factor 3, subunit A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107581:
Gene Information
Type Protein coding
Genomic Location Chromosome 26:39585658-39616179
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061515 ENSBTAP00000053182
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.
Predicted by orthology
Total 78 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0001732 formation of translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016020 membrane
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
L13a-mediated translational silencing of Ceruloplasmin expression pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Translation initiation complex formation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Initiation pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Gene Expression pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
KEGG
RNA transport pathway
RNA transport pathway
INOH
PID NCI
IL2 signaling events mediated by PI3K
Cross-References
SwissProt
TrEMBL E1B7R4
UniProt Splice Variant
Entrez Gene 506564
UniGene Bt.110528 Bt.18768 Bt.89059
RefSeq NM_001206314
HUGO HGNC:3271
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059385
GenPept
RNA Seq Atlas 506564