Version 5.4
Bos taurus Gene: TIAL1
Summary
InnateDB Gene IDBG-640377.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TIAL1
Gene Name nucleolysin TIAR
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004080
Encoded Proteins
IDBP-692639
TIA1 cytotoxic granule-associated RNA binding protein-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151923:
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:40041404-40060834
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005331 ENSBTAP00000005331
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0017091 AU-rich element binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007281 germ cell development
GO:0008284 positive regulation of cell proliferation
GO:0017145 stem cell division
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000151923
View Gene Order
ENSMUSG00000030846
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F2Z4H8
UniProt Splice Variant
Entrez Gene 614540
UniGene
RefSeq NM_001193056 XM_005225787
HUGO HGNC:11804
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059399
GenPept
RNA Seq Atlas 614540

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca