Bos taurus Gene: AP1S1
Summary
InnateDB Gene IDBG-640411.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AP1S1
Gene Name AP-1 complex subunit sigma-1A
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014468
Encoded Proteins
AP-1 complex subunit sigma-1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106367:
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:36180839-36185662
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019237 ENSBTAP00000019237
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0009615 response to virus
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005905 coated pit
GO:0016020 membrane
GO:0030117 membrane coat
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Golgi Associated Vesicle Biogenesis pathway
Immune System pathway
Clathrin derived vesicle budding pathway
MHC class II antigen presentation pathway
trans-Golgi Network Vesicle Budding pathway
Adaptive Immune System pathway
Lysosome Vesicle Biogenesis pathway
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
MHC class II antigen presentation pathway
Nef mediated downregulation of MHC class I complex cell surface expression pathway
Lysosome Vesicle Biogenesis pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
Adaptive Immune System pathway
Immune System pathway
HIV Infection pathway
The role of Nef in HIV-1 replication and disease pathogenesis pathway
Host Interactions of HIV factors pathway
Disease pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Lysosome Vesicle Biogenesis pathway
Immune System pathway
Golgi Associated Vesicle Biogenesis pathway
MHC class II antigen presentation pathway
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Adaptive Immune System pathway
KEGG
Lysosome pathway
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt Q1JQ98
TrEMBL
UniProt Splice Variant
Entrez Gene 768053
UniGene Bt.4315
RefSeq NM_001077110 XM_005225239
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC116132
GenPept AAI16133
RNA Seq Atlas 768053