InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PCOLCE

Summary

InnateDB Gene

IDBG-640552.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PCOLCE

Gene Name

procollagen C-endopeptidase enhancer 1 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020528

Encoded Proteins

IDBP-692827

procollagen C-endopeptidase enhancer 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106333:
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:36490771-36495789

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000027347

ENSBTAP00000027347

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding
GO:0008201	heparin binding
GO:0016504	peptidase activator activity

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005576	extracellular region
GO:0005581	collagen trimer
GO:0005615	extracellular space
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome