Version 5.4
Bos taurus Gene: EEF1A2
Summary
InnateDB Gene IDBG-640639.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EEF1A2
Gene Name Elongation factor 1-alpha 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021685
Encoded Proteins
IDBP-692924
Elongation factor 1-alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101210:
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:54623917-54631595
Strand Forward strand
Band
Transcripts
ENSBTAT00000028899 ENSBTAP00000028899
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006412 translation
GO:0006414 translational elongation
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005853 eukaryotic translation elongation factor 1 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000101210
View Gene Order
ENSMUSG00000016349
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_1477
Eukaryotic Translation Elongation pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_71
Gene Expression pathway
KEGG
hsa03013
RNA transport pathway
mmu03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q32PH8
TrEMBL
UniProt Splice Variant
Entrez Gene 515233
UniGene Bt.33930
RefSeq NM_001037464 XM_005214699
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108110
GenPept AAI08111
RNA Seq Atlas 515233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca