InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MTTP

Summary

InnateDB Gene

IDBG-640936.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTTP

Gene Name

Microsomal triglyceride transfer protein large subunit

Synonyms

MTP

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011944

Encoded Proteins

IDBP-693240

Microsomal triglyceride transfer protein large subunit

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138823:
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:26376148-26433473

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015850

ENSBTAP00000015850

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005319	lipid transporter activity
GO:0005515	protein binding
GO:0008289	lipid binding

Biological Process

GO:0006497	protein lipidation
GO:0006629	lipid metabolic process
GO:0006641	triglyceride metabolic process
GO:0006810	transport
GO:0006869	lipid transport
GO:0042157	lipoprotein metabolic process
GO:0042632	cholesterol homeostasis
GO:0042953	lipoprotein transport