Bos taurus Gene: RAC1
InnateDB Gene IDBG-641023.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAC1
Gene Name Ras-related C3 botulinum toxin substrate 1
Species Bos taurus
Ensembl Gene ENSBTAG00000009233
Encoded Proteins
Ras-related C3 botulinum toxin substrate 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 25:38832485-38841319
Strand Forward strand
ENSBTAT00000012170 ENSBTAP00000012170
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019899 enzyme binding
GO:0030742 GTP-dependent protein binding
GO:0031996 thioesterase binding
GO:0051022 Rho GDP-dissociation inhibitor binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0002093 auditory receptor cell morphogenesis
GO:0003382 epithelial cell morphogenesis
GO:0006184 GTP catabolic process
GO:0006897 endocytosis
GO:0006911 phagocytosis, engulfment
GO:0006972 hyperosmotic response
GO:0007010 cytoskeleton organization
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007411 axon guidance
GO:0010592 positive regulation of lamellipodium assembly
GO:0015031 protein transport
GO:0016358 dendrite development
GO:0016477 cell migration
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021831 embryonic olfactory bulb interneuron precursor migration
GO:0030032 lamellipodium assembly
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030334 regulation of cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0031529 ruffle organization
GO:0032707 negative regulation of interleukin-23 production
GO:0034446 substrate adhesion-dependent cell spreading
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0043652 engulfment of apoptotic cell
GO:0045216 cell-cell junction organization
GO:0048532 anatomical structure arrangement
GO:0048813 dendrite morphogenesis
GO:0048870 cell motility
GO:0051668 localization within membrane
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060263 regulation of respiratory burst
GO:0071526 semaphorin-plexin signaling pathway
GO:0071542 dopaminergic neuron differentiation
GO:0072659 protein localization to plasma membrane
GO:0090103 cochlea morphogenesis
GO:0097178 ruffle assembly
Cellular Component
GO:0001891 phagocytic cup
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0019897 extrinsic component of plasma membrane
GO:0030027 lamellipodium
GO:0032587 ruffle membrane
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042470 melanosome
GO:0042995 cell projection
GO:0070062 extracellular vesicular exosome
No orthologs found for this gene
DAP12 interactions pathway
Signaling by Wnt pathway
Sema4D in semaphorin signaling pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Activation of Rac pathway
Factors involved in megakaryocyte development and platelet production pathway
Signaling by GPCR pathway
Costimulation by the CD28 family pathway
CD28 dependent Vav1 pathway pathway
Inactivation of Cdc42 and Rac pathway
DCC mediated attractive signaling pathway
L1CAM interactions pathway
Sema4D induced cell migration and growth-cone collapse pathway
Sema4D mediated inhibition of cell attachment and migration pathway
Netrin-1 signaling pathway
VEGFA-VEGFR2 Pathway pathway
Translocation of GLUT4 to the plasma membrane pathway
Hemostasis pathway
Immune System pathway
Platelet activation, signaling and aggregation pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
Signal transduction by L1 pathway
EPH-Ephrin signaling pathway
CD28 co-stimulation pathway
Signal Transduction pathway
VEGFR2 mediated vascular permeability pathway
GPVI-mediated activation cascade pathway
Cell-Cell communication pathway
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Ephrin signaling pathway
Axon guidance pathway
beta-catenin independent WNT signaling pathway
NRAGE signals death through JNK pathway
PCP/CE pathway pathway
GPCR downstream signaling pathway
EPH-ephrin mediated repulsion of cells pathway
DSCAM interactions pathway
Signalling by NGF pathway
Signaling by VEGF pathway
G alpha (12/13) signalling events pathway
Adaptive Immune System pathway
p75 NTR receptor-mediated signalling pathway
EPHB-mediated forward signaling pathway
Signaling by SCF-KIT pathway
Innate Immune System pathway
FCERI mediated MAPK activation pathway
DAP12 signaling pathway
Fc epsilon receptor (FCERI) signaling pathway
Semaphorin interactions pathway
Developmental Biology pathway
Sema3A PAK dependent Axon repulsion pathway
Membrane Trafficking pathway
Signaling by Robo receptor pathway
SwissProt P62998
UniProt Splice Variant
Entrez Gene 281440
EMBL AF175262 BC103061 DAAA02058341
GenPept AAF00714 AAI03062
RNA Seq Atlas 281440