Bos taurus Gene: RAD52 | |||||||
---|---|---|---|---|---|---|---|
Summary | |||||||
InnateDB Gene | IDBG-641049.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | RAD52 | ||||||
Gene Name | DNA repair protein RAD52 homolog | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000005225 | ||||||
Encoded Proteins |
DNA repair protein RAD52 homolog
DNA repair protein RAD52 homolog
|
||||||
Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000002016:
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. [provided by RefSeq, Jul 2008] The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014] |
||||||
Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 5:108209678-108235391 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
|
||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
|
||||||
Gene Ontology | |||||||
Molecular Function |
|
||||||
Biological Process |
|
||||||
Cellular Component |
|
||||||
Orthologs | |||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
Homologous DNA pairing and strand exchange pathway
Homologous Recombination Repair pathway
Double-Strand Break Repair pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
DNA Repair pathway
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Double-Strand Break Repair pathway
Homologous DNA pairing and strand exchange pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
DNA Repair pathway
Homologous Recombination Repair pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
|
||||||
KEGG |
Homologous recombination pathway
Homologous recombination pathway
|
||||||
INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | A2VE43 F1MM43 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 512897 | ||||||
UniGene | Bt.20457 | ||||||
RefSeq | NM_001024525 XM_005207234 XM_005207235 XM_005207236 XM_005207237 XM_005207238 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | BC133563 DAAA02014592 | ||||||
GenPept | AAI33564 | ||||||
RNA Seq Atlas | 512897 | ||||||