Bos taurus Gene: MAD1L1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-641345.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | MAD1L1 | ||||||||||||
Gene Name | mitotic spindle assembly checkpoint protein MAD1 | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000002474 | ||||||||||||
Encoded Proteins |
mitotic spindle assembly checkpoint protein MAD1
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000002822:
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 25:41535263-41778055 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
Mitotic Spindle Checkpoint pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Amplification of signal from the kinetochores pathway
Cell Cycle Checkpoints pathway
Mitotic Metaphase and Anaphase pathway
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Cell Cycle Checkpoints pathway
Amplification of signal from the kinetochores pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Spindle Checkpoint pathway
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal pathway
Mitotic Anaphase pathway
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KEGG |
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
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INOH | |||||||||||||
PID NCI |
C-MYB transcription factor network
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Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Bt.43533 | ||||||||||||
RefSeq | NM_001102044 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||