Version 5.4
Bos taurus Gene: PEX26
Summary
InnateDB Gene IDBG-641377.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PEX26
Gene Name peroxisome assembly protein 26
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011826
Encoded Proteins
IDBP-693734
peroxisome assembly protein 26
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000215193:
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:109855401-109860640
Strand Forward strand
Band
Transcripts
ENSBTAT00000052262 ENSBTAP00000052887
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0032403 protein complex binding
GO:0051117 ATPase binding
Biological Process
GO:0016558 protein import into peroxisome matrix
GO:0045046 protein import into peroxisome membrane
Cellular Component
GO:0005777 peroxisome
GO:0005779 integral component of peroxisomal membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000067825
View Gene Order
ENSG00000215193
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
mmu04146
Peroxisome pathway
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QPK4
UniProt Splice Variant
Entrez Gene 537878
UniGene Bt.92630
RefSeq NM_001101172
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149365 DAAA02014629
GenPept AAI49366
RNA Seq Atlas 537878

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca