InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ITGB6

Summary

InnateDB Gene

IDBG-641392.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ITGB6

Gene Name

Integrin beta-6

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009080

Encoded Proteins

IDBP-693762

Integrin beta-6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115221:
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:36256325-36348759

Strand

Forward strand

Band

Transcripts

ENSBTAT00000011972

ENSBTAP00000011972

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001618	virus receptor activity
GO:0004872	receptor activity
GO:0005178	integrin binding

Biological Process

GO:0006954	inflammatory response
GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0007275	multicellular organismal development
GO:0009615	response to virus
GO:0016032	viral process

Cellular Component

GO:0008305	integrin complex
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043235	receptor complex
GO:0070062	extracellular vesicular exosome