Version 5.4
Bos taurus Gene: BT.45290
Summary
InnateDB Gene IDBG-641439.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.45290
Gene Name pyridoxal phosphate phosphatase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000030255
Encoded Proteins
IDBP-693802
pyridoxal phosphate phosphatase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241360:
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:110000368-110006138
Strand Forward strand
Band
Transcripts
ENSBTAT00000016505 ENSBTAP00000016505
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0031072 heat shock protein binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007088 regulation of mitosis
GO:0008152 metabolic process
GO:0030836 positive regulation of actin filament depolymerization
GO:0031247 actin rod assembly
GO:0032465 regulation of cytokinesis
GO:0071318 cellular response to ATP
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0032587 ruffle membrane
GO:0070062 extracellular vesicular exosome
GO:0070938 contractile ring
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
null
View Gene Order
ENSG00000241360
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00750
Vitamin B6 metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MW60
UniProt Splice Variant
Entrez Gene 506308
UniGene Bt.45290
RefSeq NM_001035035
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02014631
GenPept
RNA Seq Atlas 506308

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca