InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NCOA6

Summary

InnateDB Gene

IDBG-641936.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NCOA6

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007930

Encoded Proteins

IDBP-694367

nuclear receptor coactivator 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198646:
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:64639066-64726460

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000010424

ENSBTAP00000010424

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 83 interaction(s) predicted by orthology.

Predicted by orthology
Total	83 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0046966	thyroid hormone receptor binding

Biological Process

GO:0006352	DNA-templated transcription, initiation
GO:0006974	cellular response to DNA damage stimulus
GO:0007420	brain development
GO:0007507	heart development
GO:0030099	myeloid cell differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060716	labyrinthine layer blood vessel development