Version 5.4
Bos taurus Gene: BT.36110
Summary
InnateDB Gene IDBG-642274.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.36110
Gene Name NACHT, LRR and PYD domains-containing protein 5
Synonyms MATER; NALP5
Species Bos taurus
Ensembl Gene ENSBTAG00000013247
Encoded Proteins
IDBP-694717
NACHT, LRR and PYD domains-containing protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 18648497
[Homo sapiens] NLRP5 is a part of the NLRP (Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing) family, has a role in apoptosis and inflammation.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171487:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63668487-63683298
Strand Forward strand
Band
Transcripts
ENSBTAT00000017623 ENSBTAP00000017623
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0001701 in utero embryonic development
GO:0007566 embryo implantation
GO:0008152 metabolic process
GO:0009566 fertilization
GO:0009887 organ morphogenesis
GO:0031647 regulation of protein stability
GO:0034613 cellular protein localization
GO:0043487 regulation of RNA stability
GO:0043623 cellular protein complex assembly
GO:0070997 neuron death
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0043234 protein complex
GO:0045179 apical cortex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000171487
View Gene Order
ENSMUSG00000015721
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.36110
RefSeq NM_001007814
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca