Bos taurus Gene: TSG101 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-642417.3 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | TSG101 | ||||||||||||||||||||
Gene Name | tumor susceptibility gene 101 protein | ||||||||||||||||||||
Synonyms | |||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||
Ensembl Gene | ENSBTAG00000013563 | ||||||||||||||||||||
Encoded Proteins |
tumor susceptibility gene 101 protein
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074319:
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 29:26450457-26492046 | ||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||
Band | |||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 128 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH |
TCR pathway
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REACTOME |
Membrane binding and targetting of GAG proteins pathway
Late Phase of HIV Life Cycle pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
Synthesis And Processing Of GAG, GAGPOL Polyproteins pathway
HIV Life Cycle pathway
HIV Infection pathway
Assembly Of The HIV Virion pathway
Budding and maturation of HIV virion pathway
Disease pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
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KEGG |
Endocytosis pathway
Endocytosis pathway
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INOH | |||||||||||||||||||||
PID NCI |
Internalization of ErbB1
Glucocorticoid receptor regulatory network
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Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | A3KN51 | ||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 507659 | ||||||||||||||||||||
UniGene | Bt.1666 Bt.62898 Bt.67546 | ||||||||||||||||||||
RefSeq | NM_001097995 | ||||||||||||||||||||
HUGO | |||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | |||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | BC133615 DAAA02062983 | ||||||||||||||||||||
GenPept | AAI33616 | ||||||||||||||||||||
RNA Seq Atlas | 507659 | ||||||||||||||||||||