Version 5.4
Bos taurus Gene: SIAE
Summary
InnateDB Gene IDBG-642597.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIAE
Gene Name sialate O-acetylesterase precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009412
Encoded Proteins
IDBP-695065
sialate O-acetylesterase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110013:
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:28485872-28523643
Strand Reverse strand
Band
Transcripts
ENSBTAT00000030292 ENSBTAP00000030276
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001681 sialate O-acetylesterase activity
Biological Process
GO:0002682 regulation of immune system process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000110013
View Gene Order
ENSMUSG00000001942
View Gene Order
Cross-References
SwissProt
TrEMBL F1N0F2
UniProt Splice Variant
Entrez Gene 507461
UniGene Bt.7116
RefSeq NM_001045968 XM_005226787 XM_005226788 XM_005226789 XM_005226790
HUGO HGNC:18187
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02063076
GenPept
RNA Seq Atlas 507461

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca