Version 5.4
Bos taurus Gene: BT.53859
Summary
InnateDB Gene IDBG-643080.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53859
Gene Name F-box/LRR-repeat protein 12
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000025148
Encoded Proteins
IDBP-695604
F-box/LRR-repeat protein 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127452:
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:15511711-15518457
Strand Reverse strand
Band
Transcripts
ENSBTAT00000035207 ENSBTAP00000035085
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000127452
View Gene Order
ENSMUSG00000066892
View Gene Order
Cross-References
SwissProt
TrEMBL G3MW06
UniProt Splice Variant
Entrez Gene 617304
UniGene Bt.53859
RefSeq NM_001040600 XM_005200913
HUGO HGNC:13611
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019432
GenPept
RNA Seq Atlas 617304

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca