Bos taurus Gene: KCNB1
Summary
InnateDB Gene IDBG-643177.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNB1
Gene Name potassium voltage-gated channel subfamily B member 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000027320
Encoded Proteins
potassium voltage-gated channel, Shab-related subfamily, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158445:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:78194165-78304515
Strand Reverse strand
Band
Transcripts
ENSBTAT00000039169 ENSBTAP00000038969
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005244 voltage-gated ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005267 potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Voltage gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Neuronal System pathway
Potassium Channels pathway
Metabolism pathway
Integration of energy metabolism pathway
Metabolism pathway
Regulation of insulin secretion pathway
Potassium Channels pathway
Neuronal System pathway
Voltage gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
KEGG
Taste transduction pathway
Taste transduction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BDC5
UniProt Splice Variant
Entrez Gene 539528
UniGene Bt.111508 Bt.39909
RefSeq NM_001192269
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036833
GenPept
RNA Seq Atlas 539528