Bos taurus Gene: CTDSP1
Summary
InnateDB Gene IDBG-643822.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTDSP1
Gene Name carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008362
Encoded Proteins
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144579:
This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:107130648-107135774
Strand Forward strand
Band
Transcripts
ENSBTAT00000011010 ENSBTAP00000011010
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008420 CTD phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006470 protein dephosphorylation
GO:0045665 negative regulation of neuron differentiation
GO:0050768 negative regulation of neurogenesis
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Coregulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.6646
RefSeq NM_001192440 XM_005202838
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas