InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RAB11B

Summary

InnateDB Gene

IDBG-643823.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAB11B

Gene Name

Ras-related protein Rab-11B

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002475

Encoded Proteins

IDBP-696413

Ras-related protein Rab-11B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185236:
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:18249534-18259141

Strand

Forward strand

Band

Transcripts

ENSBTAT00000003206

ENSBTAP00000003206

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0001881	receptor recycling
GO:0006184	GTP catabolic process
GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0032402	melanosome transport
GO:0033572	transferrin transport
GO:0035773	insulin secretion involved in cellular response to glucose stimulus
GO:0044070	regulation of anion transport
GO:0045054	constitutive secretory pathway
GO:0045055	regulated secretory pathway
GO:0071468	cellular response to acidity
GO:1990126	retrograde transport, endosome to plasma membrane
GO:2000008	regulation of protein localization to cell surface
GO:2001135	regulation of endocytic recycling

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005768	endosome
GO:0008021	synaptic vesicle
GO:0016020	membrane
GO:0030054	cell junction
GO:0030670	phagocytic vesicle membrane
GO:0030672	synaptic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0045202	synapse
GO:0045335	phagocytic vesicle
GO:0055037	recycling endosome
GO:0055038	recycling endosome membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Mus musculus

Gene ID

Gene Order

ENSG00000185236

View Gene Order

ENSMUSG00000077450

View Gene Order

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa04144

Endocytosis pathway

hsa04962

Vasopressin-regulated water reabsorption pathway

mmu04144

Endocytosis pathway

mmu04962

Vasopressin-regulated water reabsorption pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Bt.4347

RefSeq

NM_001035391

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

GenPept

RNA Seq Atlas