Version 5.4
Bos taurus Gene: TACC3
Summary
InnateDB Gene IDBG-643897.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TACC3
Gene Name transforming acidic coiled-coil-containing protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011044
Encoded Proteins
IDBP-696496
transforming, acidic coiled-coil containing protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000013810:
This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:109636203-109645418
Strand Forward strand
Band
Transcripts
ENSBTAT00000054961 ENSBTAP00000052867
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0001666 response to hypoxia
GO:0008283 cell proliferation
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0022027 interkinetic nuclear migration
GO:0030097 hemopoiesis
GO:0030953 astral microtubule organization
GO:0032886 regulation of microtubule-based process
GO:0042994 cytoplasmic sequestering of transcription factor
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000013810
View Gene Order
ENSMUSG00000037313
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
mmu03013
RNA transport pathway
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
ilk_pathway
Integrin-linked kinase signaling
Cross-References
SwissProt
TrEMBL A6QL93
UniProt Splice Variant
Entrez Gene 506194
UniGene Bt.59859
RefSeq NM_001100305
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC147883 DAAA02018566
GenPept AAI47884
RNA Seq Atlas 506194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca