InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DES

Summary

InnateDB Gene

IDBG-644007.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DES

Gene Name

Desmin

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005353

Encoded Proteins

IDBP-696616

Desmin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175084:
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:108075460-108082534

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007041

ENSBTAP00000007041

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0042802	identical protein binding

Biological Process

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005882	intermediate filament
GO:0005916	fascia adherens
GO:0030018	Z disc
GO:0031594	neuromuscular junction
GO:0042383	sarcolemma
GO:0043292	contractile fiber