Version 5.4
Bos taurus Gene: SLC4A7
Summary
InnateDB Gene IDBG-644049.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC4A7
Gene Name sodium bicarbonate cotransporter 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018227
Encoded Proteins
IDBP-696653
solute carrier family 4, sodium bicarbonate cotransporter, member 7
IDBP-696657
solute carrier family 4, sodium bicarbonate cotransporter, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000033867:
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:1746286-1877841
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065868 ENSBTAP00000053881
ENSBTAT00000024265 ENSBTAP00000024265
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005452 inorganic anion exchanger activity
GO:0008509 anion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006820 anion transport
GO:0021747 cochlear nucleus development
GO:0046666 retinal cell programmed cell death
GO:0060117 auditory receptor cell development
GO:0061299 retina vasculature morphogenesis in camera-type eye
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000033867
View Gene Order
ENSMUSG00000021733
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19298
Bicarbonate transporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.36774
RefSeq NM_001098926 XM_005222404
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca