Version 5.4
Bos taurus Gene: OBSL1
Summary
InnateDB Gene IDBG-644075.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OBSL1
Gene Name obscurin-like protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000040338
Encoded Proteins
IDBP-696685
Obscurin-like 1Uncharacterized protein
IDBP-696689
Obscurin-like 1Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124006:
Cytoskeletal adaptor proteins function in linking the internal cytoskeleton of cells to the cell membrane. This gene encodes a cytoskeletal adaptor protein, which is a member of the Unc-89/obscurin family. The protein contains multiple N- and C-terminal immunoglobulin (Ig)-like domains and a central fibronectin type 3 domain. Mutations in this gene cause 3M syndrome type 2. Alternatively spliced transcript variants encoding different isoforms have been found in this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:108203750-108225840
Strand Reverse strand
Band
Transcripts
ENSBTAT00000060992 ENSBTAP00000053524
ENSBTAT00000038198 ENSBTAP00000038013
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007030 Golgi organization
GO:0007088 regulation of mitosis
GO:0034067 protein localization to Golgi apparatus
GO:0050775 positive regulation of dendrite morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:1990393 3M complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124006
View Gene Order
ENSMUSG00000026211
View Gene Order
Cross-References
SwissProt
TrEMBL E1BNH9 F6QPC8 Q0VC42
UniProt Splice Variant
Entrez Gene 511087
UniGene Bt.43804
RefSeq NM_001075491
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120362 DAAA02005948
GenPept AAI20363
RNA Seq Atlas 511087
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca