Version 5.4
Bos taurus Gene: LPIN2
Summary
InnateDB Gene IDBG-644174.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPIN2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012060
Encoded Proteins
IDBP-696812
lipin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101577:
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:37561435-37590398
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015997 ENSBTAP00000015997
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0008195 phosphatidate phosphatase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0016311 dephosphorylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000101577
View Gene Order
ENSMUSG00000024052
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121238
Synthesis of PC pathway
REACT_120919
Synthesis of PE pathway
REACT_1190
Triglyceride Biosynthesis pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_120870
Phospholipid metabolism pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_111217
Metabolism pathway
REACT_200828
Depolymerisation of the Nuclear Lamina pathway
REACT_160255
Nuclear Envelope Breakdown pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_199009
Synthesis of PE pathway
REACT_207335
Synthesis of PC pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_237947
Triglyceride Biosynthesis pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
hsa00561
Glycerolipid metabolism pathway
mmu00564
Glycerophospholipid metabolism pathway
mmu00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BCN1
UniProt Splice Variant
Entrez Gene 514448
UniGene Bt.109723 Bt.110815 Bt.41830
RefSeq XM_002697792 XM_005196743 XM_005224287 XM_005224288 XM_592307
HUGO HGNC:14450
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02056719 DAAA02056720
GenPept
RNA Seq Atlas 514448

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca