Version 5.4
Bos taurus Gene: DOCK10
Summary
InnateDB Gene IDBG-644199.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOCK10
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000581
Encoded Proteins
IDBP-696819
dedicator of cytokinesis 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135905:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:113649874-113891180
Strand Reverse strand
Band
Transcripts
ENSBTAT00000038166 ENSBTAP00000037982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0030334 regulation of cell migration
GO:0032319 regulation of Rho GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000135905
View Gene Order
ENSMUSG00000038608
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
cdc42_reg_pathway
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL E1B7C4
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:23479
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02006063 DAAA02006064 DAAA02006065 DAAA02006066 DAAA02006067 DAAA02006068
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca