Version 5.4
| Bos taurus Gene: EBI3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-644295.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EBI3 | ||||||||
| Gene Name | interleukin-27 subunit beta precursor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000012829 | ||||||||
| Encoded Proteins |
interleukin-27 subunit beta
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105246:
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:21033476-21040668 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
IL27-mediated signaling events
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | A6QPV0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 514933 | ||||||||
| UniGene | Bt.20904 | ||||||||
| RefSeq | NM_001100365 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC149502 DAAA02019612 DAAA02019613 DAAA02019614 | ||||||||
| GenPept | AAI49503 | ||||||||
| RNA Seq Atlas | 514933 | ||||||||