Bos taurus Gene: BT.17885
Summary
InnateDB Gene IDBG-644306.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.17885
Gene Name fos-related antigen 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006194
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175592:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2008]
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:44673879-44679325
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008136 ENSBTAP00000008136
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006355 regulation of transcription, DNA-templated
GO:0007296 vitellogenesis
GO:0031668 cellular response to extracellular stimulus
GO:0060674 placenta blood vessel development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Wnt signaling pathway pathway
Osteoclast differentiation pathway
Wnt signaling pathway pathway
Osteoclast differentiation pathway
INOH
CD4 T cell receptor signaling pathway
CD4 T cell receptor signaling pathway
PID NCI
Calcium signaling in the CD4+ TCR pathway
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Downstream signaling in naïve CD8+ T cells
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Validated targets of C-MYC transcriptional activation
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL E1BNB5
UniProt Splice Variant
Entrez Gene 531389
UniGene Bt.17885
RefSeq NM_001205985
HUGO HGNC:13718
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02063574
GenPept
RNA Seq Atlas 531389