Version 5.4
Bos taurus Gene: EXOG
Summary
InnateDB Gene IDBG-644334.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOG
Gene Name nuclease EXOG, mitochondrial
Synonyms ENDOGL1
Species Bos taurus
Ensembl Gene ENSBTAG00000019305
Encoded Proteins
IDBP-696971
endo/exonuclease (5'-3'), endonuclease G-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157036:
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]
This gene encodes an endo/exonuclease with 5\'-3\' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5\' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:11906823-11928456
Strand Forward strand
Band
Transcripts
ENSBTAT00000025704 ENSBTAP00000025704
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000737 DNA catabolic process, endonucleolytic
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157036
View Gene Order
ENSMUSG00000042787
View Gene Order
Cross-References
SwissProt
TrEMBL E1BAZ9
UniProt Splice Variant
Entrez Gene 524343
UniGene Bt.62558
RefSeq NM_001206213
HUGO HGNC:3347
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053650
GenPept
RNA Seq Atlas 524343

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca